A1 & A2-mjölk

[Mata]

Det här tycker jag är intressant och undrar om någon vet hur det är med de svenska lantaraserna och de moderna svenska korasernas mjölk och hur det kommer sig att de moderna raserna som nämns här skiljer sig från de äldre nämnda.

In the case of traditional breeds such as Guernseys and Jerseys, it is probably also more digestible. This is relatively recent and still disputed science, but the commonest type of milk in Britain (bar the Channel Islands), the US, and much of Europe bar France is produced by black-and-white Friesian and Holstein cattle and contains a type of protein known as A1. Traditional breeds and cows in Africa and Asia tend to produce A2 milk, as do horses, goats, buffalo – and humans.

De länkar till en artikel på Weston Price's hemsida och här kommer ett citat just om detta:

All proteins are long chains of amino acids that have many “branches” coming off different parts of the main chain. Beta-casein is a chain of 229 amino acids with proline at postion 67—at least the proline is there in “old-fashioned” cows. These cows with proline at number 67 are called A2 cows, and are the older breeds of cows (such as Jerseys, Asian and African cows). Some five thousand years ago, a mutation occurred in this proline amino acid, converting it to histidine. Cows that have this mutated beta-casein are called A1 cows, which include more modern breeds like Holsteins.

The side chain that comes off amino acid 67 is called BCM 7. BCM 7 is a small protein (called a peptide) that is a very powerful opiate and which has some undesirable effects on animals and humans. What’s important here is the fact that proline has a strong bond to BCM 7 which helps keep it from getting into the milk, so that essentially no BCM 7 is found in the urine, blood or GI tract of old-fashioned A2 cows.

On the other hand, histidine, the mutated protein, only weakly holds on to BCM 7, so it is liberated in the GI tract of animals and humans who drink A1 cow milk, and it is found in significant quantity in the blood and urine of these animals.

Woodford describes research showing that the opiate BCM 7 can cause neurological impairment in animals and people exposed to it, especially autistic and schizophrenic changes. BCM 7 interferes with the immune response, and injecting BCM 7 into animal models has been shown to provoke Type 1 diabetes. Dr. Woodford presents research showing a direct correlation between a population’s exposure to A1 cow’s milk and the incidence of auto-immune disease, heart disease (BCM 7 has a pro-inflammatory effect on the blood vessels), type-1 diabetes, autism, and schizophrenia. What really caught my eye is the finding that BCM 7 selectively binds to the epithelial cells in the mucous membranes (such as in the nose) and stimulates mucus secretion.

For reasons that are unclear historically, once this mutation occurred many thousands of years ago, the A1 beta-casein gene spread rapidly in many countries in the western world. Some have speculated that the reason for this wide spread of A1 cows is that the calves drinking A1 milk and exposed to the opiate BCM 7 are more docile than their traditional brethren (in effect, they were stoned). This theory is only speculation, of course. But what is true is that basically all American dairy cows have this mutated betacasein and are predominantly A1 cows.

http://www.westonaprice.org/thumbs-up-reviews/devil-in-the-milk

Läs gärna allt, det är mycket intressant tycker jag, men jag kan ju inte länka till hela artikeln, hehe... Jag är väldigt nyfiken på vad som gäller för de olika svenska raserna.

[kurt]

Genetisk variation av betydelse för mjölkkvalitet i Rödkullerasen

http://ex-epsilon.slu.se:8080/archive/00001221/01/283_Petra_Umeland.pdf

Genetisk variation i mjölkens sammansättning, art- resp. rasvariation

http://stud.epsilon.slu.se/1319/1/ragnmark_v_100614.pdf

[Mata]

Jag  hittade redan den första studien, intressant! Ska kolla andra länken. Tack! Om rödkullans mjölk:

De två vanligast förekommande varianterna av β-kasein är A1 och A2, av vilka
A1-varianten är vanligast hos de flesta nordeuropeiska raser. Den högsta frekvensen av A2
återfinns hos Guernseyrasen. B-allelen förekommer bara i låga frekvenser hos nästan alla
undersökta populationer, där den högsta frekvensen återfinns hos populationer besläktade med
Brown Swiss och hos Jerseypopulationer. A3-allelen förekommer i låg frekvens i ett flertal
nordeuropeiska raser. Rödkullor har en något högre frekvens av A1 än A2 och en låg frekvens
av B-varianten medan ingen A3-allel påträffades i populationen

http://ex-epsilon.slu.se:8080/archive/00001221/01/283_Petra_Umeland.pdf

Lite intressant fanns att finna även här:

Standardvarianterna på Beta-kasein är A1 och A2 men vi fann även en B-variant hos fjällrasen. När vi gjorde testen 1996-97 sa Anne Lundén vid SLU att det fanns en misstanke att B-varianten, som vi då funnit hos två tjurar, var en möjlig faktor vid uppkomst av juvenil diabetes. Senare har detta dementerats, alltså behöver man inte vara rädd för tjurar med B-varianten ur mjölkkvalitetssynpunkt. Nästan alla raser har A1 och A2 i någotsånär liknande delar. A2 antas öka med en allt högre proteinhalt i mjölken. B-varianten ska vara en utspjälkning från A2, men man kan ännu inte säga om den är bra eller dålig. En del forskare tror att A2-mjölk är skonsammare att dricka för folk med ”mjölkmage”, medan andra säger att det har någon betydelse.

http://www.fjallko.se/index.php?option=com_eventtableedit&view=default&Itemid=115

Håhåhjaja... Ju mer jag läser, desto mer inser jag att jag måste läsa mycket mer om jag ska få något vettigt grepp om detta. Det tycks finnas många heta åsikter, det är intressant att veta vad som är sant och vetenskap och vad som endast är teorier.
Om någon är bra på detta ämne så skriv gärna...

[Mata]

Ingen som vet mer om detta? Nu har jag kommit i kontakt med detta ett par gånger till.

http://www.amazon.com/Dont-Drink-A1-Milk-peptide/dp/0979698731

blication Date: July 8, 2011
Don’t Drink A1 Milk !! is an expose’ of the potential health hazards of drinking Type A1 cow’s milk, and the implications for the dairy industry, government, and , most importantly, the consumers. We now know that Type A1 cow’s milk genetically differs from the original A2 milk, and can generate the casomorphin peptide, BCM-7 … the devil in the milk. The BCM-7 molecule can attach itself to the insulin-producing beta cells in the pancreas, prompting an autoimmune destruction of the beta cells, leading to diabetes. It is a strong oxidant, and can oxidize LDL cholesterol, contributing to plague build-up in the arteries. It is also a powerful morphine-like opiate, and can pass through the blood-brain barrier, promoting neurological disorders such as schizophrenia and autism. The evidence is credible and compelling, and cannot be ignored. Our dairy industry has decided not to confront the enormous implications to their status quo, and does not want you to know about this issue. Our various governments and regulatory agencies have chosen to ‘bury their heads in the sand’, claiming that the BCM-7 hypothesis is not ‘proven’ and that no risk assessment or protective action is warranted. Dairy farmers in the U.S., Canada, and Europe know little about this issue. Ironically, the dairy farmers in New Zealand, where the research originated, are quietly converting their herds to A2-only producers. Almost all of the milk produced and sold in the U.S. is Type A1 or is contaminated with A1. The author suggests that what is at stake is more than simply a challenge to the dairy industry. Even more important is our health, and that of our children, and of generations to come. And what about the increasing millions who suffer and will suffer from diabetes, heart disease, and neurological disorders? He proposes that it may not be so much a matter of what science finally concludes … although this is extremely important … but may be more a matter of consumers knowing the truth, being protected, and having a choice. Yet there is a positive side to this new knowledge … we may suddenly have at our fingertips a key to eliminating a significant cause of chronic disease and the opportunity to uplift our human health to an even higher level. An urgent call for accountability and action is warranted. Consumers are asked to place their vote in both the political arena and the marketplace to insist on transparency, courage, and integrity on the part of the dairy industry, government, and science to correct this unacceptable dilemma.

"Devil in the Milk: Illness, Health and the Politics of A1 and A2 Milk"

This groundbreaking work is the first internationally published book to examine the link between a protein in the milk we drink and a range of serious illnesses, including heart disease, Type 1 diabetes, autism, and schizophrenia.

These health problems are linked to a tiny protein fragment that is formed when we digest A1 beta-casein, a milk protein produced by many cows in the United States and northern European countries. Milk that contains A1 beta-casein is commonly known as A1 milk; milk that does not is called A2. All milk was once A2, until a genetic mutation occurred some thousands of years ago in some European cattle. A2 milk remains high in herds in much of Asia, Africa, and parts of Southern Europe. A1 milk is common in the United States, New Zealand, Australia, and Europe.

In Devil in the Milk, Keith Woodford brings together the evidence published in more than 100 scientific papers. He examines the population studies that look at the link between consumption of A1 milk and the incidence of heart disease and Type 1 diabetes; he explains the science that underpins the A1/A2 hypothesis; and he examines the research undertaken with animals and humans. The evidence is compelling: We should be switching to A2 milk.

A2 milk from selected cows is now marketed in parts of the U.S., and it is possible to convert a herd of cows producing A1 milk to cows producing A2 milk.

This is an amazing story, one that is not just about the health issues surrounding A1 milk, but also about how scientific evidence can be molded and withheld by vested interests, and how consumer choices are influenced by the interests of corporate business.

[Mata]

Äntligen har jag hittat lite mer intressant info om detta...

http://voices.yahoo.com/the-a2-milk-controversy-7294524.html

Här är slutet på den intressanta texten:

In other words, A1-A2 research has not been corroborated by any official government study or review, nor is it substantiated by direct clinical research. The evidence given is circumstantial and based upon broad epidemiological research that associates populations with A1 milk that have many other associations common to them. There are many other possible associations to explain the diseases that A1 milk is purported to cause.

Furthermore, significant support and promotion of the A1-disease association appears to originate from and potentially profit a corporation whose patents control the conversion and delivery of A2 milk to the marketplace. While this association might be incidental, it does provide a dark cloud over the subject.